CDL-HM427F-100μg / 询价
CDL-HM427F-500μg / 询价
CDL-HM427F-500μgx2 / 询价
FITC-Labeled Human CD27 Ligand/CD70 Trimer Protein
Recombinant FITC-Labeled Human CD27 Ligand/CD70 Trimer Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Leu50-Pro193 [Accession | P32970-1].
The protein has a predicted MW of 51.8 kDa. Due to glycosylation, the protein migrates to 63-68 kDa based on Bis-Tris PAGE result.
Excitation Wavelength: 490 nm
Emission Wavelength: 520 nm
> 95% as determined by Bis-Tris PAGE
Less than 1EU per μg by the LAL method.
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
FITC-Labeled Human CD27 Ligand Trimer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Immobilized FITC-Labeled Human CD27 Ligand Trimer, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human CD27, hFc Tag with the EC50 of 76.2ng/ml determined by ELISA.
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
CD70 molecule; CD70; TNFSF7; CD27 Ligand; CD27-L; CD27LG; Ki-24 antigen; TNFSF7G
(1)Buchan S L , Rogel A , Al-Shamkhani A. The immunobiology of CD27 and OX40 and their potential as targets for cancer immunotherapy[J]. Blood, 2017:blood-2017-07-741025.
